Week 4 Injury Report: Alvin Kamara out. CMC is set to play. Dalvin Cook, Gabe Davis, Marquis Brown are questionable

Godwin (hamstring) is questionable for Sunday’s game against the Chiefs after managing limited practices Wednesday and Friday this week. As early as Sunday morning, there is optimism that Godwin will be able to play. Whether he would handle a regular workload is another matter, however, considering he only made it through the first half of the first game against the Cowboys before being sidelined. Julio Jones (knee), assuming he plays through his questionable tag, Russell Gage, who is also questionable but likely to play with his hamstring problem, and Scotty Miller and Cole Beasley could help absorb him workload saved by Godwin. St. Brown (ankle) will not play in Sunday’s game against the Seahawks after missing practice all week. The second-year star’s absence naturally creates a significant void in Detroit’s passing game, as he has brought in 33 targets through three games. With colleague DJ Chark (ankle) also ruled out Josh Reynolds (ankle), Kalif Raymond, Quintez Cephus and even TJ Hockenson benefited to varying degrees. Thomas (foot) will not play in Sunday’s game in London against the Vikings after missing practice all week. Thomas’ absence is of course a significant subtraction for the Saints’ offense, which will be led by Andy Dalton in place of Jameis Winston (back/ankle). Jarvis Landry, who is questionable with an ankle injury but appears to have a strong chance to play, is likely to follow many of Thomas’ short-to-mid-range routes, with Tre’Quan Smith also enjoying a shot opportunity. Allen (hamstring) will remain out for Sunday’s game against the Jaguars despite playing a pair of limited practices before missing Friday’s session. Mike Williams, Joshua Palmer and DeAndre Carter should continue to serve as Justin Herbert’s top three wideouts against Jacksonville. Brown (foot) is doubtful for Sunday’s game against the Panthers after ending the week with limited practice on Friday. However, according to early reports Sunday, Brown will suit up and should once again be the clear-cut leading receiver for Kyler Murray after recording 17 targets in Week 3, though he will be joined by Rondale Moore for first time this season. . Gallup (knee) is not on an injury designation for Sunday’s game against the Commanders, leaving him in line to at least serve at No. 3 receiver against Washington, possibly cutting into Noah Brown’s snaps. Davis (ankle) is questionable for Sunday’s game against the Ravens after sitting out a pair of limited practices in Thursday’s missed period. According to early Sunday, Davis is expected to play with the issue for a second straight game after logging an impressive 86 snaps in the Week 3 loss to the Dolphins. Hopkins will serve the fourth game of his six-game season-opening suspension Sunday. Kyler Murray plans to partner with Marquise Brown (foot), rookie Rondale Moore (hamstring) and Greg Dortch as his starting wideout three. Charak (ankle) was downgraded to out for Sunday’s game against the Seahawks after playing a pair of limited practices surrounding a missed session Thursday. Chark had entered the weekend as questionable, but his updated status, coupled with the confirmed absence of Amon-Ra St. Brown (ankle), leaves Josh Reynolds as the de facto No. 1 receiver against Seattle. Gaige (hamstring) is questionable for Sunday’s game against the Chiefs after ending the week by missing Friday’s practice. Gage is likely to continue playing with his hamstring problem, which he has dealt with to some extent since camp, and could split the No. 3 receiver snaps with Julio Jones (knee) if the veteran suits up. but he has managed his workload. Jones (knee) is questionable for Sunday’s game against the Chiefs, but finished the week with a missed practice after being limited on Wednesday and Thursday. According to early reports Sunday, the team is optimistic Jones and fellow wideout Chris Godwin (hamstring) can both suit up for Kansas City. If Jones is out, however, Russell Gage would be the full-time No. 3 receiver for as long as he plays through his injury, as expected. Landry (ankle) is doubtful for London’s clash with the Vikings on Sunday after finishing the week with two limited practices. If the veteran suits up, he’ll be in line for an expanded role with Michael Thomas (foot) on the sidelines, especially with Landry capable of handling many of the short- to mid-range targets his absent teammate often sees. Renfrow (concussion) will not play in Sunday’s game against the Broncos after missing practice all week. In Renfrow’s second straight absence, Mack Hollins, who exploded for eight receptions for 158 yards and a touchdown against the Titans in Week 3 with a workload of 63 snaps, should once again serve as the No. 2 receiver. with Keelan Cole likely stepping up. third on the depth chart. Meyers (knee) was downgraded for Sunday’s game against the Packers after practicing on a limited basis all week. Meyers’ absence will once again give extra opportunities to DeVante Parker, Kendrick Bourne and Nelson Agholor, though the trio will get passes from Brian Hoyer instead of Mac Jones (ankle). Green (knee) will not play in Sunday’s game against the Panthers after missing practice all week. In his absence, Andy Isabella is projected to be the No. 4 wideout for Arizona against Carolina. Jones (ankle) is questionable for Sunday’s game against the Eagles but returned to limited practice Friday after missing Thursday’s session. According to early Sunday morning, Jones is expected to play. Moore (calf) is questionable for Sunday’s game against the Panthers after practicing on a limited basis all week, but early reports Sunday suggested he will make his season debut against Carolina. The second-year wideout could immediately play a major role, given that AJ Green (knee) is already ruled out and Marquise Brown (foot) could be less than full health. Valdes-Scantling (abdomen) is doubtful for Sunday’s game against the Buccaneers after limited meetings Wednesday and Friday around a Thursday absence. According to reports Saturday night, Valdes-Scantling is expected to suit up and fill the usual role of No. 2 receiver. If there was a setback, Mecole Hardman would likely be the most immediate beneficiary. Reynolds (ankle) is questionable for Sunday’s game against the Seahawks, but finished the week with two limited practices after starting the week with a missed session Wednesday. Assuming he fits, Reynolds, who has plenty of experience working with quarterback Jared Goff, could play a significant role with both Amon-Ra St. Brown as well as DJ Chark sidelined against Seattle with ankle injuries. Toney (hamstring) is out for Sunday’s game against the Bears after missing practice all week. With Toney out, as well as Wan’Dale Robinson (knee) and Sterling Shepard (IR-knee), Kenny Golladay, Darius Slayton and David Sills will be in line for some extra opportunities behind Richie James. Shepard (knee) on injured reserve Wednesday after suffering a torn ACL in Monday night’s Week 3 loss to the Cowboys, an injury that will sideline him for the remainder of the season. As part of Week 4, his absence will push Richie James into a de facto No. 1 receiver role, while Kenny Golladay and Darius Slayton may also finally see a significant amount of snaps, considering Kadarius Toney (hamstring ) and Wan’Dale Robinson (knee) are also out. Watson, who missed the Week 3 win over the Buccaneers with a hamstring injury, will play in Sunday’s game against the Patriots after finishing the week with two full practices. Perriman (knee) is doubtful for Sunday’s game against the Chiefs after missing practice all week. In his possible absence, Scotty Miller and Jaelon Darden could both help fill Perriman’s downfield role. Philips (shoulder) is questionable for Sunday’s game against the Colts after practicing on a limited basis all week. If Philips returns after a one-game absence, he could split the No. 3 receiver spot with Nick Westbrook-Ikhine. Shenault (hamstring) is questionable for Sunday’s game against the Cardinals, but managed limited practices on both Wednesday and Friday. If Shenault, who posted a 3-90-1 line in Week 3 against the Saints, sits out, Rashard Higgins, who has plenty of experience working with Baker Mayfield from his Browns days, would step up to No. 4 receiver role. Robinson (knee) is out for Sunday’s game against the Bears after missing practice all week. With Kadarius Toney (hamstring) also out and Sterling Shepard (knee) on injured reserve, Richie James, Kenny Golladay, Darius Slayton and David Sills should be New York’s top four wideouts. Jones (hamstring) is questionable for Sunday’s game against the Giants, but returned to a full practice Friday. According to early reports Sunday, Jones is expected to suit up and make his NFL debut while likely being the No. 4 receiver. Kumerow (ankle) will not play in Sunday’s game against the Ravens after missing practice all week. Khalil Shakir is likely to serve as the No. 5 receiver if Buffalo chooses to keep that many wideouts active.